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SCIENTIFIC BASIS OF a New Hypothesis: Is the Cavitation Phenomenon the Mechanism for Formation of Plaques in Coronary Arteries? Protocol of a New Study.

Thach Nguyen

Abstract

In current literature, there is no confirmed mechanism for the formation and growth of atherosclerotic plaques. In reference to each individual person, the entire arterial tree is exposed to atherogenic effects of systemic risk factors and yet only a few arteries develop plaques. These plaques are observed in the coronary arteries in which they are clustered in the proximal segment of the left anterior descending artery (LAD), left circumflex (LCX), and the proximal and segments of the right coronary artery (RCA). Why is there such a pattern of spatial distribution? As seen in fluid dynamics and industrial hydraulics, the damage on the inside surface of pipes is proved to be caused by cavitation or collapse of air bubbles, a natural phenomenon that could also be similarly seen in a pattern of lightness and darkness. Could the cavitation or the ruptures of the bubbles be the mechanism of formation

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References

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