Blastocyst implantation requires the best communication between the mother’s uterus and a competent embryo. Even before the embryo enter the uterus, the endometrial tissue undergoes the process of decidualization to support the anchoring of the blastocyst and provides the blastocyst with nutrition until the fully functional placenta is formed. In this review, I summarize all the molecular and morphological events necessary for the decidualization in mice and human.
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