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NOVEL SYNTHESIS AND CHARACTERIZATION OF ANTIBACTERIAL ACTIVITY OF SILVER AND GOLD NANOPARTICLES SYNTHESIZED FROM ARCTIUM LAPPA LIN ROOT’S EXTRACTS

Truong Nguyen

Abstract

In this study, Silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs) were synthesized by a simple and eco-friendly process: using extracts from roots of Arctium lappa Linn (Burdock) as a reducing agent for both two substances AgNO3 and HAuCl4. Modern analytical techniques including UV-Vis, TEM, FT-IR, XRD and EDX were used to analyze the properties of AgNPs and AuNPs. The synthesized AgNPs from the extracts showed the antimicrobial activity with the diameter of inhibition zone for Bacillus subtilis, Agrobacterium tumefaciens, Staphylococcus aureus, Escherichia coli and Trichoderma harzianum is 6.5mm; 6.5mm; 7.0mm; 7.0mm and 10.0mm, respectively. More interestingly, our results showed the minimum inhibitory concentration (MIC) to bacteria as well as fungi is significantly low compared to antibiotics ampicillin. In detail, it is 0.11; 0.22; 0.32; 1.08 and 2.16μg/μL for Bacillus subtilis, Agrobacterium tumefaciens, Staphylococcus aureus, Escherichia coli and Trichoderma harzianum, respectively. AuNPs did not show the antimicrobial activity on both five species used in this study. Our study revealed that Arctium lappa Lin root’s extracts could be further considered as a highly potential substance in the process to synthesize AgNPs or other nanoparticles with the strongly antimicrobial properties without causing the toxicity to the body.

 

Key words: Silver nanoparticles, Gold nanoparticles, Novel synthesis, Arctium lappa Linn, Antibacterial activity.

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References

. Hulla J.E., Sahu S.C., Hayes A.W. (2015), "Nanotechnology: History and future", Human & experimental toxicology, 34(12), pp. 1318-1321.

. Richard J.W., Spencer B.A., McCoy L.F., Carina E.,Washington J., Edgar P. (2002), “Acticoat versus Silverlon: The Truth”, Journal of Burns and Surgical Wound Care, 1(11), pp. 11–20.

. Yuk-Shing Chan, Long-Ni Cheng, Jian-Hong Wu, Enoch Chan, Yiu-Wa Kwan, Simon Ming-Yuen Lee, George Pak-Heng Leung, Peter Hoi-Fu Yu, Shun-Wan Chan (2011), "A review of the pharmacological effects of Arctium lappa (burdock)", Inflammopharmacology, 19(5), pp.245-254.

. Shakeel Ahmed, Mudasir Ahmad, Babu Lal Swami, Saiqa Ikram (2016), "A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise", Journal of advanced research, 7(1), pp. 17-28.

. Kazuya Tsujino, Michio Matsumura (2005), "Boring deep cylindrical nanoholes in silicon using silver nanoparticles as a catalyst", Advanced Materials, 17(8), pp. 1045–1047.

. Pocurull E., Marce R.M., Borrull F. (1996), "Determination of phenolic compounds in natural waters by liquid chromatography with ultraviolet and electrochemical detection after on-line trace enrichment", Journal of Chromatography A, 738(1), pp. 1–9.

. Park S.Y., Hong S.S., Han X.H. Hwang J.S., Lee D., Ro J.S., Hwang B.Y. (2007), "Lignans from Arctium lappa and their inhibition of LPS-induced nitric oxide production", Chemical and pharmaceutical bulletin, 55(1), pp. 150-152.

. Mirghasem Hosseini, Mohamad Mohsen Momeni (2010), "Silver nanoparticles dispersed in polyaniline matrixes coated on titanium substrate as a novel electrode for electro-oxidation of hydrazine", Journal of materials science, 45(12), pp. 3304–3310.

. Kutsenko A.S., Granchak V.M. (2009), "Photochemical synthesis of silver nanoparticles in polyvinyl alcohol matrices", Theoretical and Experimental Chemistry, 45(5), pp. 313–318.

. Paulsen, E. (2002), "Contact sensitization from Compositae‐containing herbal remedies and cosmetics", Contact Dermatitis, 47(4), pp. 189-198.

. Poovathinthodiyil Raveendran, Jie Fu, Scott L. Wallen (2003), "Completely Green Synthesis and Stabilization of Metal Nanoparticles", Journal of the American Chemical Society, 125(46), pp. 13940–13941.

. Kumar V. G., Gokavarapu S. D., Rajeswari A., Dhas T. S., Karthick V., Kapadia Z., Tripti Shrestha, Barathy I.A., Anindita Roy, Sinha S. (2011), "Facile green synthesis of gold nanoparticles using leaf extract of antidiabetic potent Cassia auriculata", Colloids and Surfaces B: Biointerfaces, 87(1), pp. 159-163.

. Dipak Kumar Bhui, Ajay Misra (2012),"Synthesis of worm like silver nanoparticles in methyl cellulose polymeric matrix and its catalytic activity",Carbohydrate Polymers, 89(3), pp. 830–835.

. Maria Starowicz, Barbara Stypuła, Jacek Banas (2006), "Electrochemical synthesis of silver nanoparticles", Electrochemistry Communications, 8(2), pp. 227–230.

. Tamayo C., Richardson M.A., Diamond S., Skoda I. (2000), "The chemistry and biological activity of herbs used in Flor-Essence (TM) herbal tonic and Essiac (TM)", Phytotherapy Research, 14(1), pp. 1-14.

. Miyamoto K. I., Nomura M., Sasakura M., Matsui E., Koshiura R., Murayama T., Furukawa T., Hatano T., Yoshida T., Okuda T. (1993), "Antitumor-activity of oenothein-B, a unique macrocyclic ellagitannin". Cancer Science, 84(1), pp. 99-103.

. Schroder H.C., Merz H., Steffen R., Muller W.E., Sarin, P.S., Trumm S., Schulz J., Eich E. (1990), "Differential in vitro anti-HIV activity of natural lignans", Zeitschrift fur Naturforschung C, 45(11-12), pp. 1215-1221.

. Dhuper S, Panda D, Nayak PL. Green synthesis and characterization of zero valent iron nanoparticles from the leaf extract of Mangifera indica. Nano Trends: J Nanotech App 2012;13(2):16–22.

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