Vol 1, No 4 (2018): TTU Review 4

Mở đầu: Troponin được xem là chỉ dấu sinh học có giá trị tiên lượng biến cố bất lợi trong bệnh lý mạch vành, tuy nhiên chưa có nhiều nghiên cứu khảo sát sự thay đổi nồng độ của hs-Troponin I trên đối tượng bệnh nhân suy tim.

Mục tiêu: Khảo sát nồng độ hs-troponin I trên bệnh nhân suy tim tại bệnh viện Đa khoa Sóc Trăng

Đối tượng- phương pháp nghiên cứu: Nghiên cứu cắt ngang. Có 168 bệnh nhân ≥18 tuổi, được chẩn đoán suy tim cấp và mạn, đang điều trị tại Khoa Nội Tim mạch, Bệnh viện Đa khoa Sóc Trăng đã tham giam nghiên cứu. Nồng độ hs-troponin I được khảo sát và tìm mối liên quan với các đặc tính mẫu.

Kết quả:. Tuổi trung bình của dân số nghiên cứu là 68 ± 14 tuổi, nữ chiếm đa số. Không có bệnh nhân suy tim độ I, phần lớn là suy tim độ II với 48,8%. Nồng độ hs-troponin I có giá trị trung vị là 14,9ng/L. Có mối tương quan thuận, yếu với hệ số tương quan r = 0,164 và có ý nghĩa thống kê (p = 0,034) giữa nồng độ troponin I và tuổi. Nồng độ troponin I cũng có mối tương quan nghịch với phân suất tống máu thất trái, với hệ số tượng quan r = -0,262, p = 0,001.

Kết luận: hs-troponin I có thể được ứng dụng trong tiên lượng và theo dõi điều trị cho bệnh nhân suy tim.

Từ khóa: Hs-troponin, suy tim, bệnh viện đa khoa Sóc Trăng

In current literature, there is no confirmed mechanism for the formation and growth of atherosclerotic plaques. In reference to each individual person, the entire arterial tree is exposed to atherogenic effects of systemic risk factors and yet only a few arteries develop plaques. These plaques are observed in the coronary arteries in which they are clustered in the proximal segment of the left anterior descending artery (LAD), left circumflex (LCX), and the proximal and segments of the right coronary artery (RCA). Why is there such a pattern of spatial distribution? As seen in fluid dynamics and industrial hydraulics, the damage on the inside surface of pipes is proved to be caused by cavitation or collapse of air bubbles, a natural phenomenon that could also be similarly seen in a pattern of lightness and darkness. Could the cavitation or the ruptures of the bubbles be the mechanism of formation

Summary

Obesity prevalence has increased constantly and reached a global epidemic proportion over recent decades¹. Obesity and accompanied metabolic disorders such as insulin resistance, diabetes and cardiovascular complications are considered as the greatest health problems in modern society contributing to the health care burden worldwide nowadays. Obesity is a complex, chronic disorder that occurs as a result of many factors including genetic, behavioral, environmental, physiological, social and cultural factors. However, the fundamental etiology could be attributed to an energy imbalance between food consumption, basal metabolism and energy expenditure which is more and more popular with the sedentary life in modern society².

The animal models are extremely important tools for studying the molecular mechanisms underlying the pathogenesis of obesity and metabolic complications as well as developing therapeutic approaches in management of obesity and metabolic disorders. In addition to obese mouse models caused by genetic mutations (e.g. ob/ob and db/db mice), the mouse model of diet-induced obesity is a polygenic model and has become one of the most important tools for understanding of obesity development and in pharmacological studies³. C57BL/6J mouse strain is considered as the most popular diet-induced obese mouse model as this mouse strain is sensitive to high fat diet and well mimics the human metabolic derangements observed in obesity development³. Unfortunately, the unavailability of inventoried diet-induced obese C57BL/6J mouse strain in Vietnam limits the local scientists in the biomedical community to do research on metabolic studies with high fat diet (HFD). We herein attempted to set up and validate a diet-induced obese mouse model of low cost and easy reproducibility using Swiss albino mouse strain which is commonly available in 

Vietnam (obtained from Pasteur Institute at Ho Chi Minh city). Successfully establishing a diet-induced obese mouse model with Swiss albino mouse strain would enable further institutional pharmacological research studies in the future.

Medical English (Med Eng) allows medical students to better prepare for their future career as well as exchange their knowledge with the world. This article points out some methods that can be used to teach this subject for medical students in Vietnam, in which the author believes that an appropriate class and curriculum should be designed so as to increase the interactions of students in the class, thus improving their speaking skill. All the while, new technologies should be used to encourage them to self-study.

In this study, Silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs) were synthesized by a simple and eco-friendly process: using extracts from roots of Arctium lappa Linn (Burdock) as a reducing agent for both two substances AgNO₃ and HAuCl₄. Modern analytical techniques including UV-Vis, TEM, FT-IR, XRD and EDX were used to analyze the properties of AgNPs and AuNPs. The synthesized AgNPs from the extracts showed the antimicrobial activity with the diameter of inhibition zone for Bacillus subtilis, Agrobacterium tumefaciens, Staphylococcus aureus, Escherichia coli and Trichoderma harzianum is 6.5mm; 6.5mm; 7.0mm; 7.0mm and 10.0mm, respectively. More interestingly, our results showed the minimum inhibitory concentration (MIC) to bacteria as well as fungi is significantly low compared to antibiotics ampicillin. In detail, it is 0.11; 0.22; 0.32; 1.08 and 2.16μg/μL for Bacillus subtilis, Agrobacterium tumefaciens, Staphylococcus aureus, Escherichia coli and Trichoderma harzianum, respectively. AuNPs did not show the antimicrobial activity on both five species used in this study. Our study revealed that Arctium lappa Lin root’s extracts could be further considered as a highly potential substance in the process to synthesize AgNPs or other nanoparticles with the strongly antimicrobial properties without causing the toxicity to the body.

Key words: Silver nanoparticles, Gold nanoparticles, Novel synthesis, Arctium lappa Linn, Antibacterial activity.

Chronic insomnia affects a significant proportion of young adults and elderly populations. Its effects are related not only social life but also the development of economy. Currently, scientists have revealed the sleep architecture and developed many strategies for treatment. Current pharmacological approaches focus primarily on Gamma Butyric Acid (GABA), the major inhibitory neurotransmitter in the central nervous system. In addition, other receptors, such as serotonin, histamine, melatonin, are also considered. In this review, we focus on sleep disorder, the sleep architecture and current treatment methods for sleep disorder.

Chuẩn mực lập và trình bày báo cáo tài chính quốc tế (IFRS) đang được hơn 120 quốc gia trên toàn thể giới sử dụng và việc các nền kinh tế mới nổi hoặc đang phát triển theo đuổi việc chuyển sang IFRS là một hướng đi khá đúng đắn. Tuy nhiên, quá trình chuyển đổi sang IFRS là cả một chặng đường dài, trong đó tác động của việc chuyển đổi sang IFRS sẽ có tác động khá lớn trong lĩnh vực giáo dục. Nghiên cứu trên đề cập đến thực trạng của việc đào tạo kế toán của các trường đại học Việt Nam hiện nay, phân tích các khó khăn trong việc giảng dạy IFRS tại các trường đại học Việt Nam cũng như đề nghị một số các giải pháp cần thiết trong việc đổi mới đào tạo kế toán.

Business philosophies have a vision, a mission, and core values. In the same way, a personal philosophy has a vision of what contributions and improvements the world can benefit from. An individual can have one’s own mission that explains how he or she can become part of that vision. The guiding principles of the mission are called core values. As the diagram illustrates, the vision is the first concept to be developed and is the most general. After the vision is the mission, which is more specific to the individual. The core values are at the center of the mission and vision. 

An individual who develops a personal philosophy in education research that defines a vision statement, mission statement, and core values, can periodically do self-evaluation to see if his or her work has been aligned to those statements and values.

This report outlines a set of proposals to form and organize an English Enrichment Club (EEC) catering to gifted students at Tan Tao High School (TTS). It is also with a long term view of institutionalizing a program catered for the gifted and talented (G&T) students at the school.